Peptide Research Reference Database
Quick-reference tool for chemical profiles, target mechanisms, and molecular weights.
BPC-157
Tissue RepairA partial sequence of human gastric juice protein studied heavily for its potent tissue-protective and regenerative capabilities in tendons, ligaments, and gut lining.
Citation: Chang, C-H., et al. "BPC-157 accelerates tendon healing." J Orthop Res, 2011.
TB-500 (Thymosin Beta-4)
Tissue RepairA synthetic fraction of Thymosin Beta-4 that promotes cellular migration, angiogenesis, and rapid wound repair by binding actin.
Citation: Philp, D., et al. "Thymosin beta4 promotes angiogenesis and wound healing." Kidney Int, 1999.
Semaglutide
A long-acting glucagon-like peptide-1 (GLP-1) receptor agonist that enhances insulin secretion, slows gastric emptying, and significantly reduces appetite.
Citation: Wilding, J. P. H., et al. "Once-Weekly Semaglutide in Adults with Overweight or Obesity." N Engl J Med, 2021.
Tirzepatide
A dual GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 receptor agonist studied for highly potent metabolic and blood sugar regulation.
Citation: Jastreboff, A. M., et al. "Tirzepatide Once Weekly for the Treatment of Obesity." N Engl J Med, 2022.
Retatrutide
An experimental triple hormone receptor agonist targeting GLP-1, GIP, and glucagon receptors to maximize fat oxidation and energy expenditure.
Citation: Jastreboff, A. M., et al. "Triple-Hormone-Receptor Agonist Retatrutide for Obesity." N Engl J Med, 2023.
CJC-1295 (No DAC / Mod GRF 1-29)
GH SecretagogueA modified version of GHRH (Growth Hormone Releasing Hormone) that stimulates pulsatile release of natural growth hormone without spike side effects.
Citation: Teichman, S. L., et al. "Prolonged stimulation of growth hormone by CJC-1295." Clin Endocrinol, 2006.
CJC-1295 with DAC
GH SecretagogueFeatures a Drug Affinity Complex (DAC) that binds to blood albumin, drastically extending the peptide's metabolic half-life to several days.
Citation: Jette, L., et al. "Human growth hormone-releasing factor analog CJC-1295 conjugates with albumin." Bioconjug Chem, 2005.
Ipamorelin
GH SecretagogueHighly selective Growth Hormone Secretagogue (GHS) that releases GH without significantly increasing appetite, cortisol, or prolactin.
Citation: Raun, K., et al. "Ipamorelin, the first selective growth hormone secretagogue." Eur J Pharmacol, 1998.
Sermorelin
GH SecretagogueA 29-amino acid truncated analog of growth hormone-releasing hormone (GHRH) studied for pediatric and age-management GH stimulation.
Citation: Walker, R. F. "Sermorelin: A clinical review of its use in GH deficiency." Clin Interv Aging, 2006.
GHK-Cu (Copper Peptide)
Aesthetic / SkinA naturally occurring copper-binding tripeptide studied for systemic wound healing, collagen synthesis, and dramatic skin anti-aging profiles.
Citation: Pickart, L., et al. "GHK-Cu as a regenerative tissue remodeling peptide." Int J Mol Sci, 2018.
PT-141 (Bremelanotide)
Neurology / MoodA synthetic melanocortin receptor agonist (primarily MC3R/MC4R) that acts on the central nervous system to treat sexual dysfunction in laboratory models.
Citation: Diamond, L. E., et al. "Efficacy of bremelanotide in models of sexual dysfunction." Urology, 2006.
MOTS-c
A mitochondrial-derived peptide that regulates metabolic homeostasis, acts as an exercise mimetic, and counters diet-induced insulin resistance.
Citation: Lee, C., et al. "The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis." Cell Metab, 2015.
Tesamorelin
GH SecretagogueA synthetic growth hormone-releasing hormone (GHRH) analog specifically cleared/studied for the reduction of visceral abdominal fat.
Citation: Falutz, J., et al. "Effects of Tesamorelin on Visceral Fat in HIV Patients." N Engl J Med, 2007.
Epitalon (Epithalon)
LongevityA synthetic tetrapeptide resembling epithalamin (pineal gland secretion) studied for telomerase activation and cellular lifespan extension in animal models.
Citation: Anisimov, V. N., et al. "Epitalon decelerates aging and suppresses carcinogenesis in mice." Ann N Y Acad Sci, 2001.
Melanotan II
Aesthetic / SkinA synthetic melanocortin receptor agonist that stimulates eumelanin production (skin tanning) and increases libido in laboratory models.
Citation: Dorr, R. T., et al. "Evaluation of Melanotan II for tanning and libido." Life Sci, 1996.
Selank
Neurology / MoodA synthetic heptapeptide derived from tuftsin, researched as an anxiolytic (anti-anxiety agent) that stabilizes cognitive performance without sedation.
Citation: Antonova, L. V., et al. "Anxiolytic effects of Selank in neuro-psychological disorders." Neurosci Behav Physiol, 2010.
Semax
Neurology / MoodAn analog of adrenocorticotropic hormone (ACTH 4-10) studied for neurogenesis, neuroprotective properties, memory retention, and ADHD research.
Citation: Gusev, E. I., et al. "Neuroprotective effects of Semax in acute stroke." Cerebrovasc Dis, 2005.
DSIP (Delta Sleep-Inducing Peptide)
Neurology / MoodA naturally occurring nonapeptide that crosses the blood-brain barrier and promotes deep slow-wave (delta) sleep architecture.
Citation: Schoenenberger, G. A., et al. "Characterization of delta sleep-inducing peptide." Proc Natl Acad Sci, 1977.
Kisspeptin-10
LongevityA powerful hormone regulator playing a core role in triggering GnRH, LH, and FSH release, studied in infertility and hypogonadism.
Citation: Dhillo, W. S., et al. "Kisspeptin-10 stimulates gonadotropin release in humans." J Clin Endocrinol Metab, 2005.
KPV
Tissue RepairA tripeptide derivative of alpha-MSH studied for extreme anti-inflammatory pathways, inflammatory bowel disease (IBD) relief, and skin recovery.
Citation: Kannengiesser, K., et al. "KPV reduces gut inflammation in acute colitis." Inflamm Bowel Dis, 2008.
ARA-290 (Cibinetide)
Tissue RepairA non-erythropoietin erythropoietin receptor agonist explored for treating neuropathic pain, sarcopenia, and peripheral nerve injury.
Citation: Brines, M., et al. "ARA 290 relieves neuropathic pain in sarcoidosis." Mol Med, 2014.
PEG-MGF
Tissue RepairPegylated Mechano Growth Factor that localizes muscle cell repair, activates muscle stem cells (satellite cells), and boosts hypertrophy.
Citation: Goldspink, G., et al. "Mechano Growth Factor (MGF) in local tissue repair." J Physiol, 2005.
IGF-1 LR3
Tissue RepairA highly potent, long-acting analog of insulin-like growth factor-1 that triggers extreme skeletal muscle protein synthesis and hyperplasia.
Citation: Tomas, F. M., et al. "Increased potency of IGF-1 LR3 in animal growth models." J Endocrinol, 1993.
Hexarelin
GH SecretagogueA potent growth hormone-releasing hexapeptide with strong cytoprotective and recovery-promoting properties in cardiovascular models.
Citation: Imbimbo, B. P., et al. "Growth hormone release by Hexarelin." Eur J Clin Pharmacol, 1994.
GHRP-2
GH SecretagogueGrowth Hormone Releasing Peptide-2 acts directly on the pituitary to stimulate physiological pulses of human growth hormone.
Citation: Bowers, C. Y., et al. "Structure-activity relationships of GHRP-2." Endocrinology, 1992.
GHRP-6
GH SecretagogueAn analog of ghrelin that stimulates robust GH release alongside dramatic appetite stimulation and gastrointestinal motility.
Citation: Popovic, V., et al. "Stimulation of growth hormone by GHRP-6." Lancet, 1990.
HGH Fragment 176-191
A small fragment of the C-terminus of human growth hormone that isolates lipid-burning mechanisms without raising blood sugar levels.
Citation: Ng, F. M., et al. "The lipolytic domain of human growth hormone (176-191)." Endocrine, 2000.
AOD-9604
A modified analog of HGH fragment 177-191 designed to actively stimulate fat loss and cartilage regeneration without glycemic impact.
Citation: Heffernan, M., et al. "The effects of human GH drug fragment AOD-9604 on obesity." Int J Obes, 2001.
Thymosin Alpha-1 (TA-1)
LongevityA naturally occurring thymic peptide studied extensively for restoration of immune function, T-cell maturation, and defense against chronic infections.
Citation: Garaci, E., et al. "Thymosin alpha1 in combination therapy for chronic viral infections." Ann N Y Acad Sci, 2007.
SS-31 (Elamipretide)
LongevityA mitochondrial-targeted peptide that stabilizes cardiolipin, boosts ATP output, and reduces harmful reactive oxygen species (ROS) in age models.
Citation: Szeto, H. H., et al. "Mitochondrial-targeted peptide SS-31 prevents oxidative damage." J Pharmacol Exp Ther, 2011.
FoxO4-DRI
LongevityA cell-permeable senolytic peptide designed to interfere with FoxO4-p53 binding, triggering selective apoptosis (cell death) in senescent cells.
Citation: Baar, M. P., et al. "Targeted clearance of senescent cells restores tissue homeostasis." Cell, 2017.
Oxytocin
Neurology / MoodA critical mammalian peptide hormone that acts as a central neurotransmitter, heavily researched for social bonding, mood, and autism models.
Citation: Heinrichs, M., et al. "Social support and oxytocin interact to suppress cortisol." Biol Psychiatry, 2003.
Cerebrolysin
Neurology / MoodA purified peptide mixture derived from porcine brain proteins, containing neurotrophic factors studied for cognitive recovery and dementia research.
Citation: Ruether, E., et al. "Efficacy of Cerebrolysin in Alzheimer's disease." Pharmacopsychiatry, 2001.
Pinealon
LongevityA synthetic tripeptide developed to restore function in pineal gland cell lines and balance circadian sleep-wake cycles.
Citation: Khavinson, V. H., et al. "Pinealon protects brain neurons from oxidative stress." Bull Exp Biol Med, 2011.
VIP (Vasoactive Intestinal Peptide)
Tissue RepairAn immunomodulatory, vasodilating hormone researched for treating lung fibrosis, severe asthma, and intestinal barrier dysfunctions.
Citation: Pozo, D., et al. "VIP as a therapeutic agent in autoimmune diseases." Trends Immunol, 2003.
Gonadorelin
LongevityA synthetic gonadotropin-releasing hormone (GnRH) used to study direct stimulation of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
Citation: Mortimer, C. H., et al. "Gonadorelin for pituitary function evaluation." Br Med J, 1974.
LL-37 (Cathelicidin)
Tissue RepairAn antimicrobial host-defense peptide with robust bactericidal, wound-healing, and skin barrier-protecting properties.
Citation: Heilborn, J. D., et al. "The antimicrobial peptide LL-37 is critical for wound healing." J Invest Dermatol, 2003.
Humanin
LongevityA mitochondrial-derived cytoprotective peptide that prevents apoptosis (cell death) in neural, vascular, and cardiac tissue lines.
Citation: Hashimoto, Y., et al. "Humanin: A novel neuroprotective factor." J Neurosci, 2001.
Follistatin-344
Tissue RepairA glycoprotein that acts as a potent myostatin inhibitor, researched for massive increases in skeletal muscle mass and muscular dystrophy therapy.
Citation: Haidet, A. M., et al. "Follistatin-344 increases muscle mass in animal models." PNAS, 2008.
Argireline (Acetyl Hexapeptide-8)
Aesthetic / SkinA cosmetic peptide modeled after the SNAP-25 protein, studied for relaxing facial muscles to reduce the depth of mechanical expression wrinkles.
Citation: Blanes-Mira, C., et al. "A synthetic hexapeptide (Argireline) with antiwrinkle activity." Int J Cosmet Sci, 2002.